Torpres is a loop diuretic (water pill) that is used to treat fluid retention (edema) in people with heart failure, liver disease, or kidney disease. Torpres is also used to treat high blood pressure (hypertension). It lowers blood pressure by removing excess salt and water from your body. Lowering of blood pressure makes it easier for your heart to pump blood around your body and puts you at a lesser risk of having a heart attack or a stroke.
Torsemide 10mg/ 20mg/ 40mg/ 100mg
MODE OF ACTION:
Torpres is part of the loop diuretics and thus, it acts by reducing the oxygen demand in the medullary thick ascending loop of Henle by inhibiting the Na+/K+/Cl- pump on the luminal cell membrane surface. This action is obtained by the binding of Torpres to a chloride ion-binding site of the transport molecule.
Torpres is known to have an effect in the renin-angiotensin-aldosterone system by inhibiting the downstream cascade after the activation of angiotensin II. This inhibition will produce a secondary effect marked by the reduction of the expression of aldosterone synthase, TGF-B1 and thromboxane A2 and a reduction on the aldosterone receptor binding
Edema Associated with Renal Disease
20 mg once a day
5 mg orally once a day; if diuresis remains inadequate after 4 to 6 weeks, titrate up to 10 mg orally once a day
This information is for registered medical practitioner only. Anyone other than medical practitioner should consult medical practitioner before using this product.