Synbeta contains amoxicillin-sulbactam, the combination is active against both beta-lactamase producer and nonproducer strains, and is effective against Gram-positive cocci (Streptococcus pneumoniae, Streptococcus pyogenes, Staphylococcus aureus of nonhospital origin), Gram-negative cocci (Neisseria gonorrhoeae, Moraxella catarrhalis and others), Gram-negative bacilli (nonhospital strains of Haemophilus influenzae, Escherichia coli and Klebsiella pneumoniae and others) and anaerobes. Its antimicrobial activity means that it is indicated in the treatment of respiratory, ear, nose and throat, urinary, dermatological and gynecological infections caused by susceptible germs, as well as in a variety of surgical situations (both as a treatment and as prophylaxis). The combination of amoxicillin sulbactam is absorbed very well orally, and its pharmacokinetic profile is very favorable, with very good tissue penetration. Synbeta is reasonably well tolerated, in a variable percentage of cases it may cause modification of intestinal transit and/or fecal consistency, which usually abates spontaneously.

Therapy Area: Antibiotic
Form: Tablet & Parenteral intravenous injection
Packaging: 1x10 tablets / 1x1 vial


Amoxycillin 250mg + Sulbactam 250mg, Amoxycillin 500mg + Sulbactam 500mg / Amoxicillin 1gm + Sulbactum 500 mg


Amoxicillin is bactericidal in nature. It acts by inhibiting the synthesis of bacterial cell walls. Cefuroxime inhibits cross-linkage between the linear peptidoglycan polymer chains, a major component of the cell wall. It binds with the penicillin-binding proteins in the cell wall of the bacteria, interferes with cross-linking between the peptidoglycan layer and competitively inhibits the transpeptidase enzyme to cross-link the peptide used in the final phase of peptidogylcan synthesis. This makes the cell wall weak, the integrity of the cell wall is destroyed, causing cell lysis and eventually cell death. Sulbactam is an irreversible inhibitor of β-lactamase; by binding & inhibiting β-lactamase produced by bacterial cells, thereby able to prevent it from reducing antibiotic activity.


  • Respiratory tract infection
  • Respiratory tract infection
  • Skin and soft tissue infections
  • Urinary tract infections
  • Urinary tract infections
  • Surgical prophylaxis


1 tablet twice a day


1g Amoxycillin/500 mg Sulbactum every 8 hours


Upto 2 years : 1/8 vial containing 1 g Amoxycillin + 500 mg Sulbactum every 8-12 hours

2-6 yeras : ¼ vial containing 1 g Amoxycillin + 500mg Sulbactum every 8-12 hours

6-12 yeras: ½ vial containing 1 g Amoxycillin + 500mg Sulbactam every 8-12 hours


This information is for registered medical practitioner only. Anyone other than medical practitioner should consult medical practitioner before using this product.

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