Amoxycillin+sulbactam
Synbeta contains amoxycillin-sulbactam, this combination is active against both beta-lactamase producer and nonproducer strains, and is effective against Gram-positive cocci (Streptococcus pneumoniae, Streptococcus pyogenes, Staphylococcus aureus of nonhospital origin), Gram-negative cocci (Neisseria gonorrhoeae, Moraxella catarrhalis and others), Gram-negative bacilli (nonhospital strains of Haemophilus influenzae, Escherichia coli and Klebsiella pneumoniae and others) and anaerobes.
The combination of amoxycillin and sulbactam is absorbed very well orally, and its pharmacokinetic profile is very favorable, with very good tissue penetration. Synbeta is reasonably well tolerated.
COMPOSITION:
Amoxycillin 250mg + Sulbactam 250mg, Amoxycillin 500mg + Sulbactam 500mg / Amoxicillin 1gm + Sulbactum 500 mg
MODE OF ACTION:
Amoxycillin is bactericidal. It works by preventing the formation of the bacterial protective covering, which is essential for the survival of bacteria, i.e, it acts by inhibiting the synthesis of the bacterial cell wall.
Sulbactam is a beta-lactamase inhibitor that reduces resistance and enhances the activity of Amoxycillin against bacteria. In other words, Sulbactam is an irreversible inhibitor of β-lactamase; by binding & inhibiting β-lactamase produced by bacterial cells, thereby able to prevent it from reducing antibiotic activity.
INDICATIONS
- Gynecological Infections
- Respiratory tract infection
- Skin and soft tissue infections
- Urinary tract infections
Dosage
Recommended Adult Dosage:
1g Amoxycillin + 500 mg Sulbactum every 8 hours
Children:
Upto 2 years: 1/8 vial containing 1 g Amoxycillin + 500 mg Sulbactum every 8-12 hours
2-6 years: ¼ vial containing 1 g Amoxycillin + 500mg Sulbactum every 8-12 hours
6-12 years: ½ vial containing 1 g Amoxycillin + 500mg Sulbactam every 8-12 hours
Disclaimer:
This information is for registered medical practitioner only. Anyone other than medical practitioner should consult medical practitioner before using this product.
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