Shadefix cream is irritation free photostable formula to treat Hyperpigmentation associated with Acanthosis Nigricans. It helps to clear the darkness and hardness related to certain body parts like neck, nape, thighs, elbows, knees, knuckles and back. It contains Novoretin is a “Swiss Quality” product that shows skin clarifying and mattifying effects. It is a pore minimizing formula which is suitable for all skin types. Also reduces retentional lesions & increases skin hydration. Lactic acid reduces the overall severity of photodamage, mottled hyperpigmentation, sallowness, and skin roughness. Glycolic acid enhances breakdown and decreases cohesiveness, causing desquamation. Urea improves hydration and water-binding capacity. Coenzyme Q-10 (CoQ10) is a naturally occurring Quinone (antioxidant) in human body which protects tissues against oxidative damage also inhibit tyrosinase activity and melanin production. It has added advantage of hyaluronic acid to promote even skin tone and plumping effect to the skin.

Therapy Area: Hyperpigmentation
Form: Cream
Packaging: 100gm tube




Novoretin™ is a water soluble natural alternative to retinol which inhibits CYP26 degradative enzyme responsible for degradation of retinoic acid. Hence Novoretin™ enhances the retention time of retinol over the skin. Alpha hydroxy acids (Lactic acid and glycolic acid) present in the formulation helps to breakdown in the keratinocyte proliferation resulting in decrease in cohesiveness and increase in smoothness of skin tissue cells. Urea and hyaluronic acid increases skin hydration by retaining moisture content in the skin. Co-Q10 is a potent antioxidant which helps to inhibit melanin synthesis in the effected tissues.


  • First line treatment for Acanthosis Nigricans
  • Safe for all skin types and body parts
  • Visibly reduces dark spots & hardness of skin
  • Treats dry & scaly skin
  • Gives hydrating & smoothening effect
  • Offers skin clarifying & mattifying effect


  • Hyperpigmentation associated with Acanthosis Nigricans
  • Neck and Nape, Knees, Elbows, Knuckles and Thigh


Twice a day followed by Sunscreen


This information is for registered medical practitioner only. Anyone other than medical practitioner should consult medical practitioner before using this product.

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