Milifast (Minocycline) an antibiotic used to treat bacterial infections. It is effective in some infections of the lungs, urinary tract, eyes, and others. It kills bacteria, which helps to improve symptoms and cure the infection. It is also used to treat infections in patients who should not receive penicillin antibiotics. Minocycline are bacteriostatic antibiotics that are considered broad-spectrum antibiotics because they are active against a wide range of aerobic and anaerobic gram-positive and gram-negative bacteria, and against other microorganisms. It is used to treat multidrug resistant Acinetobacter infections as well as MDR infections.
MODE OF ACTION:
The tetracyclines are primarily bacteriostatic and are thought to exert their antimicrobial effect by the inhibition of protein synthesis. The tetracyclines, including minocycline, have a similar antimicrobial spectrum of activity against a wide range of gram-positive and gram-negative organisms.
Minocycline enter bacterial cells through OmpF and OmpC porins by coordinating with cations like magnesium.
This allows Minocycline into the periplasm where they dissociate, allowing the lipophilic minocycline to diffuse into the bacterial cytoplasm. Minocycline prevent aminoacyl-tRNA from binding to the 30S ribosome, inhibiting protein synthesis in bacteria.
- Respiratory Tract Infection
- Urinary Tract Infection
- Skin and Skin Structure Infections
- Chlamydial Infection
- Acute Ishchemic Stroke
200mg IV initially followed by 100mgIV every 12 hrs.
Above 8 yrs of age, 4mg/kg IV initially followed by 2 mg/kg IV every 12 hrs.
This information is for registered medical practitioner only. Anyone other than medical practitioner should consult medical practitioner before using this product.