Alpha Ketoanalogues

KETOALFA-DS is 1st time in India tablet which comes in a strength of two conventional alpha ketoanalogues tablet to reduce the increased pill burden in CKD patients and improve their adherence to therapy. It contains all amino acids essential for uremic patients, prescribed as treatment of chronic kidney disease patients on conservative management therapy (CKD stage I, II, III).

Ketoanalogues maintains the nitrogen levels and tend to serve as one of the nutrient for CKD patients. In combination with very low protein diet/ low protein diet, the medication helps in delaying progression of kidney disease in the pre-dialysis period.

Therapy Area: Renal Medicine
Form: Tablet
Packaging: 1X10 tablet

COMPOSITION:

In CKD patients it is very important to neutralize the nitrogenous wastes to prevent further degradation of renal functions. Ketoalfa-DS, a Ketoanalogue consisting of amino acids and calcium amino acid compounds, in such patients can make use of the nitrogen in non-essential amino acids and turn them into essential amino acids so as to reduce the production of urea nitrogen and relieves the building up of nitrogenous wastes and other toxic substances in the body. Adding Ketoanalogue to very low protein diets for patients with chronic kidney disease could significantly delay dialysis initiation. Ketoanalogue supplementation during Low protein diet may reduce the risk of commencing long-term dialysis or of developing the composite outcome in patients with advanced CKD, especially when used at an appropriate dosage

MODE OF ACTION:

In CKD patients it is very important to neutralize the nitrogenous wastes to prevent further degradation of renal functions. Ketoalfa-DS, a Ketoanalogue consisting of amino acids and calcium amino acid compounds, in such patients can make use of the nitrogen in non-essential amino acids and turn them into essential amino acids so as to reduce the production of urea nitrogen and relieves the building up of nitrogenous wastes and other toxic substances in the body. Adding Ketoanalogue to very low protein diets for patients with chronic kidney disease could significantly delay dialysis initiation. Ketoanalogue supplementation during Low protein diet may reduce the risk of commencing long-term dialysis or of developing the composite outcome in patients with advanced CKD, especially when used at an appropriate dosage

SALIENT FEATURES:

  • First to launch double strength Alpha Ketoanalogue 1260 mg in India
  • Reduce pill burden for better patient compliance
  • Improved treatment outcomes and better patient adherence
  • Least medication error

INDICATIONS

  • Kidney Dysfunction
  • Chronic Kidney Disease
  • Diabetic Nephropathy

Dosage

  • 40mg/kg body weight 2-3 times a day
  • Duration – as long as the GFR is between 5 and about 15 mL/min

Disclaimer:

This information is for registered medical practitioner only. Anyone other than medical practitioner should consult medical practitioner before using this product.

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