IV FUNGIN(Micafungin sodium) is a sterile, lyophilized intravenous (IV) infusion. Micafungin sodium is a semisynthetic lipopeptide (echinocandin) synthesized by a chemical modification of a fermentation product of Coleophoma empetri F-11899. Micafungin inhibits the synthesis of 1, 3-β-D-glucan, an integral component of the fungal cell wall. Intravenous micafungin an echinocandin, is approved in the EU for the treatment of adult (aged ‡16 years) and paediatric patients with invasive candidiasis and for the treatment of adult patients with oesophageal candidiasis
It does not require dose adjustments for renal or moderate hepatic dysfunction. Its safety record, favorable tolerability profile, and few drug interactions make it an important agent for the treatment of invasive fungal infections
Micafungin Sodium 50 mg
MODE OF ACTION:
Micafungin, the active ingredient in IV FUNGIN, inhibits the synthesis of 1,3-β-Dglucan, an essential component of fungal cell walls, which is not present in mammalian cells. Micafungin is a semisynthetic lipopeptide synthesized from a fermentation product of Coleophoma empetri that works as an antifungal agent. It is a glucan synthesis inhibitor of the echinocandin structural class.
- Esophageal candidiasis
- Candidial peritonitis
Indication Recommended Dose Adults
- Treatment of Candidemia, Acute Disseminated Candidiasis,
Candida Peritonitis and Abscesses infections: 100 mg/day
- Prophylaxis of Candida Infections in HSCT Recipients: 50 mg/day
- Treatment of Esophageal Candidiasis: 150 mg/day
This information is for registered medical practitioner only. Anyone other than medical practitioner should consult medical practitioner before using this product.