Fosfomycin sodium/ Fosfomycin trometamol

Fosfona (Fosfomycin sodium, Fosfomycin trometamol) is an antibiotic used to treat bacterial infections. Intravenous fosfomycin has been prescribed for various serious systemic infections, such as acute osteomyelitis, nosocomial lower respiratory tract infections, complicated urinary tract infections, bacterial meningitis, and bacteremia. However, it is only used when other common antibiotics cannot be used.Recently, fosfomycin has attracted renewed interest for the treatment of serious systemic infections caused by multidrug-resistant Enterobacteriaceae. Fosfomycin is used as an essential and beneficial option for serious systemic infections induced by multidrug-resistant Enterobacteriaceae.

Therapy Area: Antibiotic (Injectable and Orals)
Form: Parentral intravenous injection and Sachet
Packaging: 1x1 vial , 1x1 sachet

COMPOSITION:

Fosfomycin sodium 4gm, Fosfomycin trometamol 3g

MODE OF ACTION:

Fosfomycin is a bactericidal antibiotic agent. It inhibits an enzyme-catalyzed reaction in the first step of the synthesis of the bacterial cell wall.

It irreversibly inhibits enolpyruvate transferase (MurA), which prevents the formation of N-acetylmuramic acid, an essential element of the peptidoglycan cell wall.

This inhibitory action takes place at an earlier step than the action of β-lactams or glycopeptides.

INDICATIONS

  • Osteomyelitis
  • Nosocomial RTI
  • Complicated UTI
  • Bacterial Meningitis
  • Uncomplicated UTI
  • Cystitis
  • Asymptomatic bacteriuria
  • symptomatic bacteriuria
  • Prostatitis

Dosage

Injection:

4 to 12gm per day divided into 2-3 times by intravenous drip and the dose should be raised up to 16gm per day for severe infection.

 

Sachet:

  • Uncomplicated UTI– 1 sachet single dose
  • UTI by resistant pathogens– Single dose of 1 sachet on day 1,3 and 5
  • UTI in pregnant women & elderly patients– 1 sachet single dose
  • Recurrent UTI– 1 sachet every 10 days for 3 -6 months
  • Prostatitis– 1 sachet every 3 days for 21 days

Disclaimer:

This information is for registered medical practitioner only. Anyone other than medical practitioner should consult medical practitioner before using this product.

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