Fosfomycin sodium
Fosfona (Fosfomycin sodium) is an antibiotic used to treat bacterial infections. Intravenous fosfomycin has been prescribed for various serious systemic infections, such as acute osteomyelitis, nosocomial lower respiratory tract infections, complicated urinary tract infections, bacterial meningitis, and bacteremia. However, it is only used when other common antibiotics cannot be used. Recently, fosfomycin has attracted renewed interest for the treatment of serious systemic infections caused by multidrug-resistant Enterobacteriaceae. Fosfomycin is used as an essential and beneficial option for serious systemic infections induced by multidrug-resistant Enterobacteriaceae.
COMPOSITION:
Fosfomycin sodium 4gm
MODE OF ACTION:
Fosfomycin is a bactericidal antibiotic agent. It inhibits an enzyme-catalyzed reaction in the first step of the synthesis of the bacterial cell wall.
It irreversibly inhibits enolpyruvate transferase (MurA), which prevents the formation of N-acetylmuramic acid, an essential element of the peptidoglycan cell wall.
This inhibitory action takes place at an earlier step than the action of β-lactams or glycopeptides.
INDICATIONS
- Osteomyelitis
- Nosocomial RTI
- Complicated UTI
- Bacterial Meningitis
- Uncomplicated UTI
- Cystitis
- Asymptomatic bacteriuria
- Recurrent UTI
- Prostatitis
Dosage
4 to 12gm per day divided into 2-3 times by intravenous drip and the dose should be raised upto 16gm per day for severe infection.
Disclaimer:
This information is for registered medical practitioner only. Anyone other than medical practitioner should consult medical practitioner before using this product.
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