Flucloxacillin
Drug class: Narrow-spectrum beta-lactam antibiotic of the penicillin class Flucloxacillin is used to treat a wide variety of infections like Skin and soft tissue infection, Endocarditis, Pneumonia, Osteomyelitis, chest and wound infections.
It diffuses well into most tissues & organs. Effective against infections caused by methicillin-susceptible S. aureus (MSSA).
Resistant to penicillinase enzyme. Flucloxacillin should be added if staphylococcal pneumonia is suspected.
COMPOSITION:
Flucloxacillin sodium 1 gm injection
MODE OF ACTION:
Flucloxacillin acts by inhibiting the synthesis of the bacterial cell wall. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, flucloxacillin inhibits the bacterial cell wall synthesis.
It inhibits cross-linkage between the linear peptidoglycan polymer chains that make up a major component of the cell wall
INDICATIONS
- Skin and soft tissue infections: - Abscesses, cellulitis
- Respiratory tract infections: - Lower respiratory tract infections: lung abscess, pneumonia
- Bone and joint infections: - Arthritis, osteomyelitis
- Endocarditis
Dosage
Adult dose: Usual adult dose 2g every 6 hours
Children: 200 mg/kg/day in equal divided doses 4-6 hours
Disclaimer:
This information is for registered medical practitioner only. Anyone other than medical practitioner should consult medical practitioner before using this product.
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