Faropenem sodium

Faroalfa/SR (Faropenem sodium) is an oral broad-spectrum antibiotic from penem group. It is the only penem available currently for oral administration, which shares structural similarities with both penicillins and cephalosporins. It is active against both gram-positive and gram-negative aerobes and anaerobes. Faropenem is resistant to hydrolysis by nearly all beta-lactamases, including extended-spectrum all beta-lactamases and AmpC beta-lactamases. It has a low chance for resistance development and beta-lactamase induction. This makes it attractive for the treatment of community-acquired infections, and for sequential therapy following carbapenem treatment without threatening the activity of carbapenems or the entire beta-lactam class in the hospital environment. It is approved for use in the treatment of upper and lower respiratory tract infections, ear, nose and throat (ENT) infections, genito-urinary infections, skin and skin structure infections, and gynaecological infections. Faropenem is a very promising and new oral antibiotic with proven efficacy and safety for the treatment of a variety of community-acquired infections.

Therapy Area: Antibiotic (Oral Solids)
Form: Tablet
Packaging: 1x6, 1x4 tablets

COMPOSITION:

Faropenem 200mg, Faropenem 300 mg SR

MODE OF ACTION:

Faropenem is bactericidal in nature. It acts by inhibiting the synthesis of bacterial cell walls. Faropenem inhibits cross-linkage between the linear peptidoglycan polymer chains, a major component of the cell wall. It binds with the penicillin-binding proteins in the cell wall of the bacteria, interferes with cross-linking between the peptidoglycan layer, and competitively inhibits the transpeptidase enzyme to cross-link the peptide (D-alanyl-alanine) used in the final phase of peptidoglycan synthesis. This makes the cell wall weak, the integrity of the cell wall is destroyed, causing cell lysis and eventually cell death.

INDICATIONS

  • Respiratory tract infections
  • ENT infections
  • Genito-urinary infections
  • Skin & soft tissue infections
  • Gynaecological infections

Dosage

Faroalfa- Thrice a day

Faroalfa-SR- Twice a day

Disclaimer:

This information is for registered medical practitioner only. Anyone other than medical practitioner should consult medical practitioner before using this product.

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