Aztreonam is a beta-lactam antibiotic. It is used to treat selected Aztreonam-sensitive gram-negative bacteria. A monocyclic beta-lactam antibiotic originally isolated from chromo bacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. Aztreonam rapidly distributes in tissues and fluids. 56% protein bound. Safe in renal impaired patients. Potent & Effective in Gram –Ve Infections.
Aztreonam 1gm/2gm Injection
MODE OF ACTION:
The bactericidal action of aztreonam results from the inhibition of bacterial cell wall synthesis. Due to a high affinity of Aztreonam for penicillin-binding protein 3 (PBP3). By binding to PBP3, Aztreonam inhibits the third and last stage of bacterial cell wall synthesis. This causes the formation of elongation or bacterial filamentation resulting in cell lysis and cell death.
- Urinary Tract Infections
- Lower Respiratory tract infections
- Skin and skin structure infections
- Intra-abdominal infections
- Gynecologic Infections
1-2gm IV/IM q8-12hrs: not to exceed 8gm/day
This information is for registered medical practitioner only. Anyone other than medical practitioner should consult medical practitioner before using this product.