Doxybuz (Doxycycline) is a broad-spectrum antibiotic synthetically derived from oxytetracycline. This drug is a second-generation tetracycline, exhibiting lesser toxicity than first-generation tetracyclines. Doxycycline is indicated for the treatment of various infections by gram-positive and gram-negative bacteria, aerobes and anaerobes, as well other types of bacteria. Doxycycline may be used to treat a wide range of bacterial infections, depending on the results of antibiotic susceptibility testing. It is effective in some infections of the lungs, urinary tract, eyes, and others. It kills bacteria, which helps to improve your symptoms and cure the infection. It helps to improve your symptoms and cure the underlying infection.
MODE OF ACTION:
In bacterial replication, an interaction that is important for translation initiation of proteins occurs at the 3′ end of the 16S rRNA, found on the ribosome on the 30S subunit. The 30S subunit is the smaller subunit of the ribosome of prokaryotes, including bacteria.
Tetracyclines such as doxycycline are thought to inhibit translation by binding to the 16S rRNA portion of the ribosome , preventing binding of tRNA to the RNA-30S bacterial ribosomal subunit, which is necessary for the delivery of amino acids for protein synthesis. As a result of the above actions, the initiation of protein synthesis by polyribosome formation is blocked. This stops the replication of bacteria and produces a bacteriostatic effect.
- Typhus Fever
- RTI (Respiratory Tract Infection)
- UTI (Urinary Tract Infection)
- Q Fever
- Chlamydial Infection
200 mg on the first day of treatment administered in one or two infusion. Subsequent 100-200mg depending upoon the severitu of the infection.
This information is for registered medical practitioner only. Anyone other than medical practitioner should consult medical practitioner before using this product.