Fosfomycin Trometamol

Auxifos (Fosfomycin Trometamol) is an orally active, broad-spectrum bactericidal agent. It is used as a first-line agent for killing the bacteria that cause UTIs. It is active against both gram-negative and gram-positive bacteria. It is highly effective against E. Coli (bacteria that has gained resistance against several antibiotics). Fosfomycin does not develop resistance even after long-term usage.

Therapy Area: Renal Critical Care
Form: Sachet
Packaging: 1X8 gm

COMPOSITION:

Fosfomycin Trometamol 3 gm sachet

MODE OF ACTION:

Fosfomycin is a bactericidal antibiotic agent. It inhibits an enzyme-catalyzed reaction in the first step of the synthesis of the bacterial cell wall. It irreversibly inhibits enolpyruvate transferase (MurA), which prevents the formation of N-acetylmuramic acid, an essential element of the peptidoglycan cell wall. Ultimately, the first step of bacterial cell wall synthesis is disrupted.

INDICATIONS

  • Uncomplicated UTI (Acute Cystitis)
  • Recurrent UTI (3 uncomplicated UTIs in 12 months)
  • Complicated Cystitis

Dosage

Uncomplicated UTI (Acute Cystitis) – 1 sachet of 3 grams

Recurrent UTI (3 uncomplicated UTIs in 12 months) – 1 sachet of 3 grams in every 10 days for 3-6 months

Complicated Cystitis – 1 sachet of 3 grams in every 2-3 days (Total 3 sachet)

Disclaimer:

This information is for registered medical practitioner only. Anyone other than medical practitioner should consult medical practitioner before using this product.

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