AUXICASP (caspofungin acetate) is a sterile, lyophilized product for intravenous (IV) infusion that contains a semisynthetic lipopeptide (echinocandin) compound synthesized from a fermentation product of Glarealozoyensis. AUXICASP is a member of a class of antifungal drugs (echinocandins) that inhibits the synthesis of β (1, 3)-D-glucan, an integral component of the fungal cell wall. Caspofungin is a lipopeptide antifungal drug. It is a member of new class of antifungal termed as echinocandins. Caspofungin is antifungal agent with broad spectrum activity against all candida species.
Caspofungin 50 mg & 70 mg
MODE OF ACTION:
Fungal cell has 2 components which work as protective barrier as follows 1. Fungal cell wall 2. Fungal cell membrane. Beta 1,3 glucan is main component of fungal cell wall. Fungal cell membrane or plasma membrane has an enzyme known as Beta Glucan Synthase which further helps in formation of Beta 1,3 Glucan. Beta 1,3 Glucan Further combines with Chitin (Fibrillar Polysaccharide) which increases strength of fungal cell wall.
Caspofungin block the synthesis of beta 1,3 glucan of the fungal cell wall by which cell deficiency takes place. Cell wall synthesis inhibits due to Caspofungin antifungal drug.
- Invasive candiditis
- Esophageal candidiasis
- Febrile neutropenia
Loading dose of 70 mg on day 1 followed by maintenance dose of 50 mg once a day
This information is for registered medical practitioner only. Anyone other than medical practitioner should consult medical practitioner before using this product.