Cefepime + Tazobactum injection
ALFAPIME-TZ (Cefepime and Tazobactam) are indicated as a parenteral therapy for the treatment of various moderate to severe forms of infections due to susceptible beta-lactamase producing microbial organisms. Cefepime and Tazobactam combination are particularly indicated if the Cefepime monotherapy is ineffective. Cefepime and Tazobactam are prescribed for the treatment of uncomplicated skin and skin structure infections, uncomplicated and complicated urinary tract infections (UTI) and complicated intra-abdominal infections in adults and children. Cefepime is a 4th generation cephalosporin.
Cefepime 1gm + Tazobactum 125mg injection/ Cefepime 2gm + Tazobactum 250mg injection
MODE OF ACTION:
Cephalosporins are bactericidal and have the same mode of action as other beta-lactam antibiotics (such as penicillins). Cephalosporins disrupt the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity, especially in Gram-positive organisms. The final transpeptidation step in the synthesis of the peptidoglycan is facilitated by transpeptidases known as penicillin binding proteins (PBPs).
- Respiratory Tract Infection
- Urinary Tract Infection
- Skin and Skin Structure Infections
- Abdominal Infection
- Empiric therapy for febrile neutropenic patients
- Mild to Moderate Infection 1-2 g daily in 2 divided dose
- Severe Infection: Upto 4 gm daily in 2 divided dose
- Neonates : 30mg/kg 12 hrly, may increase to 50mg/kg in severe infection
This information is for registered medical practitioner only. Anyone other than medical practitioner should consult medical practitioner before using this product.
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