Alcofix IV

COMPOSITION:

Thiamine Hydrochloride (300mg) + Magnesium Oxide (375mg) + Zinc Sulphate (50mg) + Pyridoxine Hydrochloride (50mg) + Folic Acid (1.5mg) + Selenium Dioxide (200mcg) + Copper Sulphate (2mg) Tab

Each ML Contains: Thiamine Hydrochloride (250mg), Riboflavin (4mg); Pyridoxine Hydrochloride (50mg)
Injection 5ml (Part-A) + Ascorbic Acid (500mg), Nicotinamide (160mg), Anhydrous Dextrose (1000mg) Injection
5ml (Part – B)

MODE OF ACTION:

Thiamine (B1)

Alcoholics are at risk for vitamin B deficiencies because of malabsorption and a poor diet. Thiamine is one of many vitamin B deficiencies that alcoholics often experience because high intake of alcohol prevents thiamine from being broken down and properly utilized.

Pyridoxine

Vitamin B6 or pyridoxine deficiency has been associated with alcohol ingestion. Low circulating plasma vitamin B6 levels have been reported in 60% of a patient population with alcoholic cirrhosis, although only a small proportion had clinical symptoms of deficiency. Plasma levels of pyridoxal-

5′-phosphate (PLP), the biologically active form of vitamin B6, have been shown to be a reliable index of vitamin B6 nutrition and to correlate with the PLP content of erythrocytes and with such functional indices of vitamin B6 status as the tryptophan loading test and PLP saturability of red blood cell transaminases. 

Magnesium Oxide

Magnesium is an important co-factor in many thiamine dependent enzymes involved in carbohydrate metabolism, and patients may fail to respond to parenteral thiamine in the presence of hypomagnesemia.

Folic Acid

Folate deficiency is frequent among alcoholics, and low serum folate and red blood cell folate levels can be found in up to 60% of heavy drinkers. Folic acid helps the body produce new cells.

Zinc

Zinc deficiency may alter hepatocyte functions and also immune responses in inflammatory liver diseases. It may impair the activity of enzymes of the urea cycle as well as glutamine synthetase and decreased activity of these enzymes has the potential to lead to further increases in circulating and brain ammonia with the potential to cause worsening of HE.

INDICATIONS

• Alcoholic Liver Disease
• Chronic Alcoholics
• Alcohol Withdrawal
• Septic Shock Patient with Alcoholic Disorders

Dosage

Disclaimer:

This information is for registered medical practitioner only. Anyone other than medical practitioner should consult medical practitioner before using this product.