Tapentadol is in a class of medications called opiate (narcotic) analgesics. It works by changing the way the brain and nervous system respond to pain. Tapentadol extended-release tablets are used to treat severe neuropathic pain (pain caused by nerve damage) in people who have diabetes. Tapentadol is an orally available, synthetic benzenoid that acts as an agonist for the mu-opioid receptor (MOR) and inhibits the reuptake of noradrenaline, with potential anti-nociceptive activity.

Therapy Area: Renal Medicine
Form: Tablets
Packaging: 1X10


Tapentadol 50mg


Upon oral administration, Ultraniche-T binds to the MOR (Mu opioid receptor) which enhances MOR-mediated signaling, interferes with the sensation of pain and results in an analgesic effect. Ultraniche-T also inhibits the reuptake of noradrenaline, which increases the levels of noradrenaline (NA), activates the inhibitory alpha-2 receptors and results in an analgesic effect.


  • Diabetic Neuropathy pain
  • Nociceptive Pain
  • Traumatic pain
  • Post-surgical Pain


  • For general Patients: One tablet twice a day
  • For Renal Patients: Patients with CrCl >30mL/Min: One tablet Twice a day


This information is for registered medical practitioner only. Anyone other than medical practitioner should consult medical practitioner before using this product.

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