Azoalfa (Azathioprine) is a prodrug of 6-mercaptopurine. Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant. An effective immunosuppressant in treating pemphigus vulgaris, pemphigoid, eczematous disorders & actinic dermatitis and safer than steroids in long-term use.
Azathioprine 50 mg
MODE OF ACTION:
Azathioprine’s mechanism of action is not entirely understood but it may be related to inhibition of purine synthesis, along with inhibition of B and T cells, de novo pathway of purine synthesis, stops proliferation of T & B cells, 6-thioguanine triphosphate, a metabolite of azathioprine, modulates activation of rac1 when costimulated with CD28, inducing T cell apoptosis. This may be mediated through action on mitogen-activated protein kinase, NF-kappaB.
- Autoimmune disorders
- Inflammatory disorders
1-3 mg/kg daily up to 8-12 weeks
This information is for registered medical practitioner only. Anyone other than medical practitioner should consult medical practitioner before using this product.